Expression profiles of bovine genes in the rectoanal junction mucosa during colonization with Escherichia coli O157:H7.
نویسندگان
چکیده
A bovine-specific cDNA microarray was used to characterize gene expression in the bovine rectoanal junction mucosa in response to Escherichia coli O157:H7 colonization, and results were confirmed using quantitative real-time PCR. The results showed involvement of cell processes including immune response, cell structure/dynamics, signal transduction, intercellular communication, and metabolism.
منابع مشابه
Escherichia coli O157:H7 colonization at the rectoanal junction of long-duration culture-positive cattle.
Long-duration consistently Escherichia coli O157:H7 culture-positive cattle were euthanized and necropsied. Tissue and digesta from along the gastrointestinal tract (GIT) were cultured for the bacteria and examined histologically for lymphoid character. E. coli O157:H7 was detected only at the rectoanal junction mucosa and not at any other GIT location.
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عنوان ژورنال:
- Applied and environmental microbiology
دوره 73 7 شماره
صفحات -
تاریخ انتشار 2007